BDBM50433369 CHEMBL2377825

SMILES Nc1nc(Nc2ccc(cc2)S(N)(=O)=O)sc1C(=O)c1ccccc1[N+]([O-])=O

InChI Key InChIKey=JXJHPQHLHQTQQI-UHFFFAOYSA-N

Data  9 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433369   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of South Australia Cancer Research Institute

Curated by ChEMBL

LigandBDBM50433369(CHEMBL2377825)Copy SMILESCopy InChI

Affinity DataIC50:  1.10nMAssay Description:Inhibition of GST-tagged CDK2/Cyclin E (unknown origin) expressed in baculovirus expression system using GST-pRb (776 to 928 residues) as substrate m...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLMMDBPC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI